EKA - an inventory of proteins / peptides extractable from non-coding DNA
Key people: Vipin, Shiddhi, Deepthi (CSSB, University of Kerala), Ravi (Andhra University)
The EKA project was started with an aim to facilitate artificial synthesis of novel peptides and proteins from vast unexplored regions of the genome. The first version of EKA shows general features, sequence similarity, protein structure and function predictions of intergenic regions of Escherichia coli K12. The second version shall include introns, repetitive sequences, pseudogenes of model organisms.
EKA KB is based on MySQL, with a front end supported by PHP, HTML and Java. It has a search option where the user can get information on the potential function, interaction, structure and cellular localization of proteins, if expressed. The entire database can be downloaded free, in the form of flat files. In the near future, more search options like organism specific searches and pathway specific searches will be added. In future, we also aim to build a pipeline of characterizing user specific sequences from new organisms. The database will go online soon.
updated Nov. 14, 2010